Best Ingredients

Vitamin B5
(Pantothenic Acid)

The Follicle Vitalizer — Extends the Growth Phase and Prevents Premature Shedding

Vitamin B5, also known as pantothenic acid, supports follicle metabolism, cellular energy production, scalp hydration, and healthy hair cycling. Research shows dexpanthenol directly supports human hair follicle cells by extending the anagen growth phase and reducing follicular stress.

2021 Published Study
VEGF Growth Support
B5 Essential Vitamin
Vitamin B5 (Pantothenic Acid)
B5
Vitamin B5
Pantothenic Acid · Dexpanthenol
★ Extends Growth Phase
★ Supports VEGF
★ Reduces Breakage
Shop Growth Complex View The Research
Vitamin B5 (Pantothenic Acid)
B5
Vitamin B5
Pantothenic Acid · Dexpanthenol
★ Extends Growth Phase
★ Supports VEGF
★ Reduces Breakage

The Ingredient

What Is Vitamin B5?

Vitamin B5 directly supports human hair follicle cells by extending the growth phase and reducing premature follicular aging.

Vitamin B5, also known as pantothenic acid, is an essential water-soluble B vitamin that serves as a precursor to Coenzyme A (CoA) — one of the most fundamental molecules in human metabolism.

CoA is required for fatty acid synthesis, energy production, and the synthesis of steroid hormones, including those that regulate hair follicle cycling.

In hair care, B5 is most commonly encountered as dexpanthenol (D-panthenol), a provitamin that is readily converted to pantothenic acid in the body.

Dexpanthenol has a long history in hair care formulations due to its humectant properties — helping retain moisture, improve texture, and reduce breakage.

Research now shows dexpanthenol also has direct biological effects on human hair follicle cells themselves.

A 2021 study demonstrated that dexpanthenol extends the anagen growth phase, reduces apoptosis and cellular senescence, and stimulates VEGF-related follicle vascularization.

Key Benefits

Precursor to Coenzyme A Required for fatty acid synthesis, cellular energy production, and steroid hormone metabolism.

Extends the Anagen Growth Phase Dexpanthenol directly supports prolonged hair growth activity in follicle cells.

Reduces Follicle Cell Stress Shown to suppress apoptosis and reduce cellular senescence markers in dermal papilla cells.

Supports VEGF Production Stimulates vascular endothelial growth factor to improve follicle nutrient delivery and scalp circulation.

Hydrates & Protects Hair Shafts Humectant properties help retain moisture, reducing brittleness and breakage.

Clinical Evidence

The Science: Clinical
Studies & Research

Emerging research demonstrates that dexpanthenol has direct biological effects on human hair follicle cells.

STUDY 1

Human Follicle CellsAnagen SupportVEGF Activation

Dexpanthenol Elongates Anagen Phase and Prevents Cell Senescence in Human Hair Follicle Cells

Shin JY, Kim J, Choi YH, Kang NG, Lee S. · Current Issues in Molecular Biology · 2021

Dexpanthenol enhanced cell viability, reduced apoptosis markers, and stimulated anagen-inducing factors in human hair follicle cells.

Researchers observed increased proliferation markers, reduced apoptosis and senescence markers, stimulation of beta-catenin and versican pathways, suppression of TGF-beta1, and increased VEGF signaling related to follicle vascularization.

View Study →, opens in a new tab

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HAIRLOVE Products Containing
Vitamin B5

Vitamin B5 is included throughout the HAIRLOVE system to support follicle metabolism and healthy growth-phase signaling.

Front view of Growth Complex pouch, pink resealable bag with HAIRLOVE logo and 60 capsules
GrowthFollicles

Growth Complex

Contains Vitamin B5 alongside Cynatine® HNS and 7 targeted nutrients supporting healthy follicle activity and hair growth.

Front view of Inside-Out Bundle showing Growth Complex pouch and Scalp Serum bottle on white background
GrowthBundle

Inside-Out Bundle

Pairs Growth Complex with our topical Scalp Serum for dual-track internal and topical hair support.

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Editor's Note

The 2021 Shin et al. study is notable because it works directly on human hair follicle cells — making it one of the most directly relevant studies in the entire HAIRLOVE formula.

All 8 Growth Complex Ingredients

Cynatine® HNS BioPerine® Biotin Vitamin B5 Vitamin C Vitamin E Zinc Selenium